In the mitochondria NADH and QH2 are essentially oxidized by ...............since it is the terminal electron acceptor.

This question tests conceptual understanding. Review the topic carefully to determine the correct answer.

Mitochondria MCQ Questions and Answers for Practice

Welcome to our Mitochondria MCQs section, where students and exam aspirants can test their knowledge on the vital cellular structures. These multiple-choice questions are designed to help you prepare for exams, interviews, and concept revision.

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Mitochondria are often referred to as the powerhouses of the cell due to their crucial role in energy production. These MCQs cover essential topics such as the structure, function, and genetic aspects of mitochondria. You will also find questions on mitochondrial diseases and their impact on cellular processes.

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Mitochondria MCQ Questions for Practice

1. In the mitochondria NADH and QH₂ are essentially oxidized by ...............since it is the terminal electron acceptor.

oxygen
carbon dioxide
ozone
hydrogen peroxide

2. The................is between the inner and outer membranes of the mitochondria.

intracellular fluid
ATP synthase complex
intermembrane space
matrix

3. Oxidative phosphorylation requires all of the items listed below except

ATP synthase in the correct position in the membrane.
the flow of electrons from NADH and QH₂ in the membrane.
a matrix more positively charged than the intermembrane space.
a terminal electron acceptor which is H₂O in mitochondria.

4. ATP synthase is located in the...................of the mitochondrion.

inner membrane
intermembrane space
outer membrane
matrix

5. The inner mitochondrial membrane contributes to the formation of a proton gradient mainly because it

is a barrier to protons.
is rich in proteins.
is not rich in proteins.
is the location of specific transporter proteins.

6. The chemiosmotic theory is a concept that

explains the blood-brain barrier
the transport of Na⁺ and K⁺ across cell membranes is by active transport
explains how transport by facilitated diffusion reaches a saturation limit
a proton gradient that drives the formation of ATP

7. The protonmotive force is a result of

All of the above
the flow of protons within the inner mitochondrial membrane
a combination of an electrical potential and a chemical potential
the flow of electrons from the matrix to the inner membrane space

8. At one time the uncoupler 2, 4-dinitrophenol was used as a weight reducing drug. Its side-effects, including death, resulted in its discontinued use. How could this drug cause weight loss?

The uncoupler causes ATP to be produced at a much higher rate than normal and this causes weight loss.
The uncoupler is an allosteric activator of ATP synthase. This increases the rate of translocation of H⁺ and the oxidation of fuels, including fats.
The uncoupler allows the oxidation of fats from adipose tissue without the production of ATP. This allows the oxidation to proceed continuously and use up the fats.
The uncoupler inhibits the transport of pyruvate into the matrix of the mitochondria. Fats are then degraded to glycerol and subsequently to pyruvate to provide the necessary energy. Thereby depleting fat stores.

9. What feature of cytochromes makes them valuable in electron transport systems?

the iron ion
aspartate residues in the active site
the multiple alpha-helices
the porphyrin ring

10. Which has the highest reduction potential?

NADH
complex I
O₂
complex II

11. To reduce one molecule of O₂, ..............electron(s) must be passed through the electron transport chain and ..............molecule(s) of NADH is(are) oxidized.

4, 2
1, 1
4, 4
1, 2

12. Which is a component of complex I?

13. How many protons are translocated across the membrane by complex I for every pair of electrons that are passed from NADH to QH₂?

14. Which complex in the electron transport chain does not contribute to the proton gradient?

15. The terminal electron acceptor for complex III of the electron transport chain is

cytochrome C
Fe-S
Q
FAD

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